Director

Dr. Geert J.V. Poelmans, M.D./Ph.D., Founder and Director

Geert Poelmans

In September 1994, Geert Poelmans (1976) started studying medicine at the Catholic University of Leuven, Belgium, where he graduated with the University Degree of Doctor of Medicine (M.D.) in June 2002. From August 2002 until January 2009, he pursued a number of clinical training and staff level positions in Clinical Genetics, Child and Adolescent Psychiatry and Adult Psychiatry in The Netherlands (Maastricht and Doetinchem), Belgium (Leuven) and the U.K. (Cambridge and Clacton). From February 2009 until October 2011, he was an M.D. researcher and Ph.D. student at the Department of Cognitive Neuroscience of the Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, The Netherlands. His Ph.D. research was on the genetics of selected neurodevelopmental disorders and his supervisors were Professor Jan Buitelaar and Professor Barbara Franke (Radboud University Nijmegen Medical Centre), and Professor David Pauls (Psychiatric and Neurodevelopmental Genetics Unit, Harvard Medical School, Harvard University, USA). He was awarded his Ph.D. cum laude on 1 November 2011. In addition to his role as director of Drug Target ID, he is currently a Research Associate at the Department of Human Genetics, Radboud University Nijmegen Medical Centre as well as the Department of Molecular Animal Physiology, Radboud University Nijmegen, where he pursues research into genetic and translational aspects of complex disorders.

Key publications

1. Poelmans, G., Buitelaar, J.K., Pauls, D.L., Franke, B. A theoretical molecular network for dyslexia: integrating available genetic findings.Mol. Psychiatry 16, 365-382 (2011).
2. Poelmans, G., Pauls, D.L., Buitelaar, J.K., Franke, B. Integrated genome-wide association study findings: identification of a neurodevelopmental network for attention deficit hyperactivity disorder. Am. J. Psychiatry 168, 365-377 (2011).
3. Poelmans, G., Franke, B., Pauls, D.L., Glennon, J.C., Buitelaar, J.K. AKAPs integrate genetic findings for autism spectrum disorders. Translational Psychiatry 3, e270; doi:10.1038/tp.2013.48 (2013).
4. Vallès, A, Martens, G.J.M., De Weerd, P., Poelmans, G.*, Aschrafi, A.* MicroRNA-137 regulates a glucocorticoid receptor-dependent signaling network: implications for the etiology of schizophrenia. J. Psychiatry Neurosci 39, 312-320 (2014); * equal contribution.
5. Klemann, C.J.H.M.,  Martens, G.J.M., Poelmans, G.*, Visser, J.E.*  Validity of the MPTP-treated mouse as a model for Parkinson’s disease. Mol. Neurobiol. 53, 1625-1636 (2015); * equal contribution.
6. Van de Vondervoort, I.*, Poelmans, G.*, Aschrafi, A., Pauls, D.L., Buitelaar, J.K., Glennon, J.C.*, Franke, B.*  An integrated molecular landscape implicates the regulation of dendritic spine formation through insulin-related signaling in obsessive-compulsive disorder. J. Psychiatry Neurosci. 41, 140327 (2016); *equal contribution.